Effects of thyroidectomy and submaxillary sialoadenectomy on physiological parameters in the female rat

The effects of interaction of the thyroid function with the submaxillary glands on the female rat, on the body growth, weight evolution of adrenal glands, ovary and parotid glands, puberty onset, estrous cycle, fertility, gestation and offspring size, plasmatic levels of glucose, glucagon, Na+, K+ and total protein have been studied. The effects of sialadenectomy and thyroid function are both independent in all parameters, except in ovary growth, which is depressed by thyroid function when submaxillary glands are removed, and in circulating glucose, since sialadenectomy stabilizes to hypoglycemia which results from thyroidectomy.     

The geneticist and the so-called "socio cultural" familial mental retardation

Five hundred children and adolescents affected by mild mental retardation were studied together with their families with regard to a number of psycho-social, medical and genetic factors. Statistical studies were performed with these data and showed that this apparently homogeneous population could in fact be divided into three subgroups. The first and by far the largest group (66%) was constituted by a clinically normal population but in whom adverse social and cultural factors were dominant. In the second subgroup (20%) the mental retardation was much more pronounced (IQ of 50----65) and the socio-cultural and socio-economic levels were particularly low. Finally, organic causes (prematurity, dystocic, labour, etc.) seemed to constitute the principal factor explaining the retardation observed in the third subgroup (14%). The second subgroup comprising of 50 children and their families, were observed more closely; in this group 20 cases of known genetic diseases were found.     

Cytotopochemische Beiträge zum Lipidvorkommen in Vakuolen

Summary The content of vacuoles of the two yeastsEndomyces lactis andCandida utilis and of the nucleolus in the cell nucleus ofAsterias sp. have been analysed upon the occurrence of lipids. For this reason, it were contrived observations and measurements in polarization optics, and used a few cytochemical reactions for lipids, employing partly the fluorescence microscope, partly the phase contrast technique. From the behaviour of the vacuolar leptones in this reactions it is concluded that at least the vacuoles of the two yeasts contain phospholipids, and the vacuoles of the starfish nucleoli, perhaps, beside this also lipoproteins in different amounts. From preliminary measurements with the yeasts in absorption photometry, it. moreover, follows that the tested reactions do not indicate the same substances, but, verisimiliter, a different inferior group of phospholipids.

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Prof. Dr. Karl Höfler in celebration of his seventieth birthday.